Month: May 2020

Reviewed by Emily Henderson, B.Sc.May 30 2020 A combination of genetic shuffling and evolutionary selection of near-identical genetic sequences among specific bat and pangolin coronaviruses may have led to the evolution of SARS-CoV-2 and its introduction into humans, a new study suggests. The results also showed that the virus’ entire receptor binding motif (RBM), a
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Print this page TARRYTOWN, N.Y. and PARIS, May 26, 2020 /PRNewswire/ – Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announced that the U.S. Food and Drug Administration (FDA) has approved Dupixent (dupilumab) for children aged 6 to 11 years with moderate-to-severe atopic dermatitis whose disease is not adequately controlled with topical prescription therapies or when those therapies are not
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Frontline pembrolizumab doubled progression-free survival (PFS), when compared with chemotherapy, among patients with microsatellite instability–high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer in the KEYNOTE-177 study. The median PFS was 16.5 months for patients who received pembrolizumab and 8.2 months for those who received investigators’ choice of chemotherapy (one of six regimens). “In the past, no medical
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In HER2-positive breast cancer patients with brain metastases treated with trastuzumab and capecitabine, add-on tucatinib increased median overall survival from 12 months to 18.1 months in a phase 2 trial. The results were presented as part of the American Society of Clinical Oncology virtual scientific program and published simultaneously in the Journal of Clinical Oncology.
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Welcome to this week’s edition of Healthcare Career Insights. This weekly roundup highlights healthcare career-related articles culled from across the Web to help you learn what’s next. Lisa Grabl is president of the locum tenens division of CompHealth, the nation’s largest locum tenens physician staffing company and a leader in permanent and temporary allied healthcare
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Print this page KENILWORTH, N.J. & MIAMI–(BUSINESS WIRE) May 26, 2020 –Merck (NYSE: MRK), known as MSD outside the United States and Canada, and Ridgeback Biotherapeutics LP, a closely held biotechnology company, today announced that the companies have entered into a collaboration agreement to develop EIDD-2801, an orally available antiviral candidate currently in early clinical
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Print this page NORTHBROOK, Ill., May 27, 2020 /PRNewswire/ — Astellas Pharma Inc. (TSE: 4503, President and CEO: Kenji Yasukawa, Ph.D., “Astellas”) announced today that the U.S. Food and Drug Administration (FDA) has approved VESIcare LS (solifenacin succinate) oral suspension for the treatment of neurogenic detrusor overactivity (NDO) in pediatric patients aged 2 years and
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Cailin Healy, and an unidentified friend, both of Calabasas, take a selfie together as beach-goers enjoy warm summer-like weather amid state and city social distancing regulations mandated by Gov. Newsom in Huntinton Beach, CA, on April 22, 2020. Allen J. Schaben | Los Angeles Times via Getty Images As the U.S. begins to reemerge from
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Here are the coronavirus stories Medscape’s editors around the globe think you need to know about today: Social Distancing Flattened the Curve, Studies Say  Two new modeling studies indicate that social distancing interventions flattened the curve of COVID-19 hospitalizations compared with
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Almost one-third of patients with new-onset rheumatoid arthritis (RA) reported persistent unacceptable pain after 21 months of combination therapy, according to a study by Swedish researchers. A total of 29% of patients continued to have unacceptable pain, defined as a score above 40 mm on a 100 mm visual analog scale, after 21 months of
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Think dinosaurs are always so majestic and powerful-looking? Think again, because some of them look downright silly or outright questionable. Here’s a handy guide. 5 Of The Goofiest-Looking Dinosaurs That Ever Lived Thanks to iconic movies like “Jurassic Park,” we usually feel a collective “wowwww” whenever we think of the giant, ancient lizard behemoths that
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Prescription fills for hydroxychloroquine/chloroquine spiked right after COVID-19 was declared a national emergency in March, but use of the drugs still remains well above 2019 levels, based on data from more than 58,000 U.S. pharmacies. Hydroxychloroquine/chloroquine are also doing better than
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At least 1,721,750 people have been infected with coronavirus in the US and 101,617 have died, according to data from Johns Hopkins University. The US Centers for Disease Control and Prevention projects that by June 20 the death toll will reach about 123,000. The projection is based on an ensemble forecast of more than a
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Print this page NEW BRUNSWICK, NJ, May 27, 2020 — The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of Sirturo (bedaquiline). Sirturo is now indicated for use as part of combination therapy in the treatment of adult
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States across the U.S. continue to chart their own paths forward, trying to thread the needle between public health concerns and efforts to restart the economy amid mass unemployment. Another 2.1 million people filed jobless claims over the past week while continuing claims, or those who have been collecting for at least two weeks, reached 21.05 million,
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