Adding the immune checkpoint inhibitor nivolumab (Opdivo) to neoadjuvant chemotherapy dramatically increased pathologic complete response (pCR) in patients with operable lung cancer, a randomized trial showed. The pCR rate increased from 2.2% with chemotherapy alone to 24.0% with the addition of nivolumab. The between-group difference increased in an analysis limited to patients who had complete
Claudia Finkelstein, Michigan State University It’s the moment we thought we were all waiting for…or is it?We were cautiously optimistic about the end of the pandemic in view of increasing vaccine availability and decreasing case numbers after the peak in January. Then, whether due to variants, pandemic fatigue or both, cases and case positivity began
Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Several vaccine sites across the U.S. paused administration of the Johnson & Johnson COVID-19 vaccine this week after adverse reactions were reported, according to The Associated Press. On Thursday, three vaccination sites in North Carolina closed temporarily after several people had
News Clinical Trials Johnson & Johnson Statement on U.S. COVID-19 Vaccine Manufacturing New Brunswick, NJ (April 3, 2021) – Johnson & Johnson is assuming full responsibility regarding the manufacturing of drug substance for its COVID-19 vaccine at the Emergent BioSolutions Inc. Bayview facility. Specifically, the Company is adding dedicated leaders for operations and quality, and significantly
Some studies have reported the detection of ribonucleic acid (RNA) specific for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in breast milk from women who were recently infected with the virus. A new study, released on the medRxiv* preprint server, explores the relationship between viral RNA and infectious virus to clarify the occurrence of
Pfizer-BioNTech asked for authorization Friday to use their Covid-19 vaccine on 12 to 15-year-olds in the United States, which could mark a crucial next step toward achieving herd immunity. The mass vaccination of teenagers would also relieve an enormous strain on parents who are juggling the demands of homeschooling their children while keeping up with
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Shoppers wearing protective masks walk near the Dubai Mall and the Burj Khalifa skyscraper in Dubai, United Arab Emirates, on Wednesday, Jan. 27, 2021. Christopher Pike | Bloomberg | Getty Images The International Monetary Fund has revised its growth forecast upward for the Middle East and North Africa region, as countries recover from the coronavirus
Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Loss of smell, loss of taste, dyspnea, and fatigue are the four most common symptoms that healthcare professionals in Sweden report 8 months after mild COVID-19 illness, new evidence reveals. Approximately one in 10 healthcare workers experience one or more moderate-to-severe
The 24-hour news cycle is just as important to medicine as it is to politics, finance, or sports. At MedPage Today, new information is posted daily, but keeping up can be a challenge. As an aid for our readers and for a little amusement, here is a 10-question quiz based on the news of the
A new study published in the Frontiers of Psychiatry reinforces older studies that say smartphone addiction can ruin your sleep. The definition of smartphone addiction, according to those who consider themselves addicted, is “a decreased interest in face-to-face relationships, use despite knowledge of the negative consequences, impaired control over and preoccupation with their devices, and
The US Food and Drug Administration (FDA) on Friday announced its first-ever approval of an artificial intelligence device to help find colon lesions during colonoscopy. The GI Genius (Cosmo Artificial Intelligence) identifies areas of the colon where a colorectal polyp or tumor might be located. Clinicians then follow up with a closer examination and possible
Psychosocial stress – typically resulting from difficulty coping with challenging environments – may work synergistically to put women at significantly higher risk of developing coronary heart disease, according to a study by researchers at Drexel University’s Dornsife School of Public Health, recently published in the Journal of the American Heart Association. The study specifically suggests
Apr 9 2021 Curing cancer has been the dream of countless doctors and researchers over the decades. Yet some types of cancer, whether because they affect relatively few people or lack influential advocates, receive less attention and funding than others. Cells from a rare cancer known as blastic plasmacytoid dendritic cell neoplasm, shown in purple
Regardless of how you feed your baby, watching that little body so intent on taking in nourishment, all while nestled in the crook of your arm is a sight that will disappear all too soon. Even if you are nursing, the time will come when your baby will need a bottle. We found in our
In this Feb. 24, 2021, file photo provided by the Michigan Office of the Governor, Gov. Gretchen Whitmer addresses the state during a speech in Lansing, Mich. Gov. Whitmer signed at least $2.5 billion in COVID-19 relief spending Tuesday, March 9, 2021, while vetoing $650 million after Michigan Republicans did not negotiate with her and
A team of Mount Sinai surgeons in New York City earlier this year performed the world’s first human tracheal transplant surgery, the health system announced this week. News of the procedure’s success already has other patients taking note. To date, surgeons have been unable to transplant the trachea — an organ essential for speaking, breathing,
The Centers for Disease Control and Prevention (CDC) on Thursday declared racism a serious public health threat and outlined steps it will take to address it. “[I]t affects the health of our entire nation,” CDC Director Rochelle Walensky, MD, MPH, said in a statement. The CDC is the largest public health group to make that
A proportion of chronic pain patients on prescribed opioids took chances with their medications over time, such as seeking early refills or giving pills to others — but such behaviors were intermittent, not persistent, according to data from the Australian POINT study. In a group of about 1,500 people with chronic noncancer pain surveyed every
Last month, we reported on an FDA safety warning that connected Real Water-brand alkaline water to outbreaks of hepatitis. Since then the story has taken crime-novel-like twists and turns including disappearing personnel, roadblocks to keep investigators at bay, and the filing of a lawsuit or two. Outbreak and recall The investigation began when the FDA
Several students at Dartmouth’s Geisel School of Medicine in Hanover, New Hampshire, are being investigated on accusations of cheating on closed-book exams taken remotely, according to a report from a New Hampshire newspaper, the Valley News, on Wednesday. The report says the investigations started at earlier this year when a witness who was using Canvas,
Dr. Raaj Ruparel hosts this video series from the Mayo Clinic Multidisciplinary Simulation Center in Rochester, MN. In this episode learn how to help a choking infant.
CAMBRIDGE, Mass.–(BUSINESS WIRE)–Apr. 7, 2021– Moderna, Inc. (Nasdaq: MRNA), a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, today highlighted the publication of antibody persistence data out to 6 months following the second dose of the Moderna COVID-19 Vaccine in The New England Journal of Medicine. “We are pleased that this new data shows antibody persistence through 6 months following
An adaptive cognitive training program could help treat attention and working memory difficulties in children with sickle cell disease (SCD), a new study published in the of Journal of Pediatric Psychology shows. These neurocognitive difficulties have practical implications for the 100,000 individuals in the U.S. with SCD, as 20-40% of youth with SCD repeat a
In December, with two vaccines approved for emergency use, inoculations began in this country. In mid-March, a few states began relaxing their pandemic-related restrictions, including Maryland, Texas, Mississippi, Connecticut, Arizona, West Virginia and Wyoming. Recently other states including Pennsylvania and Indiana, did the same. On Jan.5, the number of daily cases reported was 235,027 By
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A health worker prepares to do tests for Covid-19 coronavirus outside a makeshift clinic in a sports stadium in Port Moresby on April 1, 2021. Gorethy Kenneth | AFP | Getty Images Misinformation on social media is hindering Papua New Guinea’s vaccination efforts. Many people are hesitant about inoculation due to false information being spread
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